Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p029 | (1) | SRF2015

Successful isolation, culture and karyotyping of equine placental cells from failed early pregnancies

Rose Belinda Vivienne , Cabrera-Sharp Victoria , Cameron Ian , Crabtree James , Crowhurst James , Firth Marvin , Ghosh Sharmila , McGladdery Andrew , Neal Huw , Pynn Jan , Pynn Oliver , Raudsepp Terje , Smith Charlie , Verheyen Kristien , Wathes D Claire , Wise Zara , de Mestre Amanda

Early pregnancy loss (EPL) in the mare is defined as loss of pregnancy between initial detection and day 65 of gestation. It occurs in 7–10% of pregnancies and yet little is known about the underlying pathologies. A lack of suitable conceptus material has limited investigation into the role of chromosomal defects in EPL. The objective of this study was to develop a method to isolate and culture placental cells isolated from failed pregnancies to enable further genetic cha...